Subarachnoid hemorrhage
Conditions
Interventions
control group:early craniotomy(8-24 hours)
experimental group:ultra-early craniotomy (<8 hours)
Sponsors
904th Hospital of Joint Logistic Support Force of PLA
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years, gender unlimited. 2. Patients with intracranial aneurysm confirmed by CTA / DSA / MRA, which is responsible for the recent subarachnoid hemorrhage. 3. Patients are in poor neurological condition (Hunt & Hess Grades IV or V) on admission. 4. Patients whose time from onset to randomization and emergency operation is less than 8 hours. 5. According to ethics committee requirements, the person responsible for the patient must agree to participate in this trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. With Pseudoaneurysm; 2. Drug addicts; 3. Patients with basic diseases that seriously affect the prognosis, long-term oral aspirin before operation, coagulation dysfunction and other diseases that affect the effect of operation; 4. With serious coagulation dysfunction; 5. With organ failure; 6. With serious psychosomatic diseases; 7. Pregnant or lactating women. 8. The persons responsible for the patient refuse to give consent to participate in this trial; 9. Patients are participating in another randomized clinical trial for treatment of SAH.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRS at 6 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-Cause Mortality witnin 90 days;Incidence of delayed cerebral infarction;Incidence of hydrocephalus;Incidence of cerebral vasospasm; | — |
Countries
China
Contacts
Public ContactYuhai Wang
Neurosurgery Department of 904th Hospital of Joint Service Support Force of PLA
Outcome results
None listed