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The effect of dexmedetomidine for anesthesia maintenance and postoperative analgesia on the non-cardiac surgery prognosis of high-risk elderly patients: a prospective, randomized, double-blind, controlled trial.

The effect of dexmedetomidine for anesthesia maintenance and postoperative analgesia on the non-cardiac surgery prognosis of high-risk elderly patients: a prospective, randomized, double-blind, controlled trial.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030566
Enrollment
Unknown
Registered
2020-03-07
Start date
2020-03-15
Completion date
Unknown
Last updated
2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative complications

Interventions

experimental group:dexmedetomidine
control group:Normal saline

Sponsors

The First Hospital of Beijing University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age more than 60-year old; 2. Patients will undergo selective non-cardiac surgery with expected surgery time >= 2 hours; 3. Revised cardiac risk index >= 3; 4. Willing to participate in this trial and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. With severe bradycardia(HR <= 50bpm), sick sinus syndrome, AVB 2 or above without pacemaker; 2. Child-Pugh grade C; 3. With renal failure (neen renal replacement therapy); 4. Patients weighing less than 50kg or more than 90kg; 5. Neurosurgery.

Design outcomes

Primary

MeasureTime frame
postoperative complications;—

Secondary

MeasureTime frame
Sleep quality;Pain intensity;Length of postoperative in-hospital stay;Medical expense;—

Countries

China

Contacts

Public ContactMu Dongliang

The First Hospital of Beijing University

mudongliang@icloud.com+86 13810702725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026