Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Gold Standard:Nucleic acid test
Index test:Nano-nasal 
COVID-19 
diagnostic 
screening 
model
Sponsors
Anhui Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: COVID-19 group: 1. Age> = 18 years old, no gender restriction; 2. Patients with covid-19 determined by gold standard; 3. Total bilirubin = 18 years old; 2. Patients with negative nucleic acid test; 3. Blood biochemical urea nitrogen <=1.25 UNL, creatinine <=1.25 UNL; Total bilirubin <=1.5 UNL, aspartate aminotransferase AST (SGOT) and alanine aminotransferase ALT (SGPT) <=2.5 UNL; 4. With Symptoms of fever and cough; 5. No smoking or drinking in the past week; 6. All patients should be informed. Healthy control group: 1. Healthy patients who were screened by the physical examination center; 2. Had no history of acute disease in the past two weeks; 3. No smoking and drinking history in the past week; 4. Patients with informed consent.
Exclusion criteria
Exclusion criteria: COVID-19 group: 1. Patients without self-awareness; 2. Patients who used drugs that can affect metabolism in the past 2 weeks, such as antibiotics (penicillins, erythromycin), hormones (deoxycortisol, dexamethasone), non-steroidal anti-inflammatory drugs (aspirin, sanitin), etc. 3. Patients with significant abnormalities in lung ventilation; 4. Pregnant or lactating women; 5. Patients with other metabolic disorders and any acute disease symptoms in the past 2 weeks. Similar symptoms group 1. Patients without knowledge; 2. With previous medical history of COVID-19. 3. Patients with other metabolic disorders and any acute disease symptoms in the past 2 weeks; 4. Patients with significant abnormalities in lung ventilation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volatile organic compounds, VOCs;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactHu Liu
Anhui Cancer Hospital
Outcome results
None listed