Chronic obstructive pulmonary disease
Conditions
Interventions
NCO group:Oxygen supply with common double lumen nasal catheter
HFNC group:Use high flow oxygen therapy
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with AECOPD and arterial blood gas pH 50 mmHg were diagnosed according to the Chinese guidelines for the diagnosis and treatment of chronic obstructive pulmonary disease (2013). 2. Aged >= 18 years; 3. Those who can obtain informed consent.
Exclusion criteria
Exclusion criteria: 1. Immediate tracheal intubation is needed: respiratory rate > 40 times / min, severe hypoxia (oxygenation index under high concentration oxygen inhalation < 150), severe respiratory acidosis pH < 7.2, consciousness disorder (Glasgow score < 8), etc; 2. There are NIV taboos: mouth and face trauma, poor sputum discharge capacity, hemodynamic instability, etc; 3. Palliative treatment is being carried out for those with poor short-term prognosis and high risk of death within 7 days; 4. Other organ failure; 5. Tracheotomy; 6. Patients with pneumothorax, hemoptysis and severe pneumonia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total time of respiratory support; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intubation rate during hospitalization;Duration of treatment and interval of NIV;ICU length of stay and total length of stay; | — |
Countries
China
Contacts
Public ContactDingyu Tan
Northern Jiangsu People's Hospital
Outcome results
None listed