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Research for the mechanism of improvement of novel coronavirus pneumonia (COVID-19) patients' pulmonary exudation by continuous renal replacement therapy

Research for the mechanism of improvement of novel coronavirus pneumonia (COVID-19) patients' pulmonary exudation by continuous renal replacement therapy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030540
Enrollment
Unknown
Registered
2020-03-06
Start date
2020-03-08
Completion date
Unknown
Last updated
2020-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

Control group:Routine treatment, CRRT only when there are emergency indications

Sponsors

Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients confirmed by 2019-nCov throat swab or other samples of nucleic acid positive; 2. Patients with clear manifestations of pulmonary exudation on chest imaging; 3. Patients requiring oxygen therapy or mechanical ventilation, ARDS (oxygenation index < 200mmHg) was diagnosed according to the Berlin standard in 2012.

Exclusion criteria

Exclusion criteria: 1. Patients with cardiopulmonary resuscitation at the end of the disease; 2. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Chest imaging;Oxygenation index;Extravascular pulmonary water;pulmonary vascular permeability index, PVPI;Inflammatory factors;Tissue kallikrein;

Secondary

MeasureTime frame
Mechanical ventilation time (days);Total hospitalization time (days);28-day all-cause mortality;

Countries

China

Contacts

Public ContactLi Shusheng

Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology

shushengli16@sina.com+86 13971086498

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026