Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients confirmed by 2019-nCov throat swab or other samples of nucleic acid positive; 2. Patients with clear manifestations of pulmonary exudation on chest imaging; 3. Patients requiring oxygen therapy or mechanical ventilation, ARDS (oxygenation index < 200mmHg) was diagnosed according to the Berlin standard in 2012.
Exclusion criteria
Exclusion criteria: 1. Patients with cardiopulmonary resuscitation at the end of the disease; 2. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chest imaging;Oxygenation index;Extravascular pulmonary water;pulmonary vascular permeability index, PVPI;Inflammatory factors;Tissue kallikrein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical ventilation time (days);Total hospitalization time (days);28-day all-cause mortality; | — |
Countries
China
Contacts
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology