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Application value of transnasal high flow nasal cannula in terminal care of cancer: a multicenter, randomized controlled, open label clinical trial

Application value of transnasal high flow nasal cannula in terminal care of cancer: a multicenter, randomized controlled, open label clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030530
Enrollment
Unknown
Registered
2020-03-06
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Terminal tumor

Interventions

control group:Intranasal oxygen inhalation

Sponsors

Chongqing Liangjiang New Area First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. The predicted survival rate of patients with tumor end-stage disease is less than 6 months (NRF score > 2); 2. The patients have dyspnea, the respiratory rate is more than 25 times / min; 3. The patients have respiratory failure in hospital (the diagnosis of respiratory failure needs to meet any of the following conditions: 1) the oxygenation index under oxygen therapy is less than 300; 2) the PaO2 under air inhalation is less than 60 MmHg; 3) if there is no blood gas analysis, it can be replaced by SpO2 =18 years; 5. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who were unable to wear hfnc during face or upper airway surgery; 2. Patients who were unable to use transnasal high flow humidification oxygen therapy due to severe nasal obstruction; 3. Respiratory and cardiac arrest requires endotracheal intubation and invasive ventilation; 4. Weak spontaneous breathing; 5. Coma.

Design outcomes

Primary

MeasureTime frame
Reduction of Borg score;Length of stay;

Secondary

MeasureTime frame
Degree of reduction of respiratory rate;Dosage of analgesics;

Countries

China

Contacts

Public ContactHu Zhong

Chongqing Liangjiang New Area First People's Hospital

Cqwshz007@163.com+86 02361103649

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026