Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
COVID-2019 patients in Tongji Hospital:none
COVID-2019 patients in Mobile field hospital:none
Medical staff in Tongji Hospital:none
Control:none
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. COVID-19 suspected or confirmed patients: meet the following suspected or confirmed case diagnostic criteria; aged between 18 and 70 years old; 1.1 Diagnostic criteria for suspected cases; 1.1.1 History of Epidemiology: (1) travel history or residence history within 14 days before the morbidity in Wuhan and its surrounding areas, or in other communities with reported cases; (2) History of contact with new coronavirus infection (positive nucleic acid test) within 14 days before morbidity; (3) Patients with fever or respiratory symptoms from Wuhan and its surrounding areas, or from communities with reported cases, had been contacted within 14 days before the morbidity; (4) Clustered morbidity (2 or more cases of fever and/or respiratory symptoms in a small area such as home, office, school class, etc. Within 2 weeks); 1.1.2 Clinical manifestations: (1) Fever and/or respiratory symptoms; (2) Having the above novel coronavirus pneumonia imaging features; (3) In the early stage of morbidity, the total number of white blood cells is normal or reduced, or the number of lymphocytes is normal or reduced; 1.1.3 Have any of the epidemiological history, and meet any 2 of the clinical signs. If there was no clear epidemiological history, it was in accordance with the 3 items in the clinical signs; 1.2 Diagnostic criteria for confirmed case Suspected cases also have one of the following etiological or serological evidence: (1) Detection of High Homology of Novel Coronavirus by Real-time Fluorescence RT-PCR; (2) Sequencing of the viral genome, which is highly homologous to known novel coronaviruses; (3) Serum specific IgM antibody and IgG antibody of new type coronavirus were positive; the specific IgG antibody of new type coronavirus in serum changed from negative to positive or increased by 4 times or more in recovery stage than in acute stage; 2. non-COVID healthy residents: Wuhan residents; non-COVID-2019 patients; 3. medical staff: age 18-70 years old and in-service hospital staff.
Exclusion criteria
Exclusion criteria: 1. COVID-19 suspected or confirmed patients: (1) Those who refuse to cooperate; (2) Pregnant women; (3)Patients with mental disorders and cognitive dysfunction. 2. non-COVID healthy residents: (1) Those who refuse to cooperate; (2) Patients with mental disorders and cognitive dysfunction. 3. medical staff: (1) Those who refuse to cooperate; (2) non-working staff; (3) Patients with mental disorders and cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nuclei acid test of SARS-CoV-2 of conjunctival swab;Nuclei acid test of SARS-CoV-2 of throat swab;Nuclei acid test of SARS-CoV-2 of peripheral blood sample;Eye symptoms;Clinical symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Previous eye diseases;Eye drop medication;Previous diseases;Chest CT; | — |
Countries
China
Contacts
Public ContactXufang Sun
Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed