Thyroid cancer
Conditions
Interventions
Sponsors
Southwest Hospital, Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 - 70 years; 2. Patients who are highly suspected of malignant thyroid nodules by imaging but whose pathological results after FNA suggest Bethesda I, II, III; 3. Other general condition is good: physical condition score 0 to 2 points; 4. Hematology: white blood cells >= 3.5 x 10^9 / L, platelets >= 100 x 10^9 / L, neutrophils >= 2.0 x 10^9 / L, hemoglobin >= 95g / L. 5. Liver function: serum bilirubin is 1.5 times the maximum normal value; ALT and AST are 1.5 times the maximum normal value. 6. Renal function: creatinine clearance >= 45ml / min. 7. Coagulation function: APTT, PT, FIB, TT showed no obvious abnormalities. 8. Heart function: Basically normal. 9. Informed consent is required, and is willing to cooperate with the project for clinical follow-up. 10. Is willing to cooperate with the provision of FNA test samples, patient imaging and postoperative pathological routines and other related medical records, and is willing to use the test data for scientific research in clinical institutions.
Exclusion criteria
Exclusion criteria: 1. Have other malignancies at the same time; 2. At the discretion of the investigator, the patient suffers from other major diseases that may affect follow-up and short-term survival; 3. Any social / psychological issues where the patient judges that the patient is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BRAF gene;SEN, SPE, ACC, AUC of ROC, NPV, PPV; | — |
Countries
China
Contacts
Public ContactXiaowei Qi
Southwest Hospital, Army Medical University
Outcome results
None listed