Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Experimental group:Ganovo/ ritonavir oral+conventional treatment
Control group:Conventional treatment
Sponsors
Shenyang Sixth People's Hospita
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years old; 2. Pneumonia patients with new coronavirus infection were confirmed to be positive by RT-PCR and clinical manifestations. The diagnosis standard refers to the diagnosis and treatment plan for pneumonia with new coronavirus infection; 3. patients with newly diagnosed respiratory system discomfort who have been hospitalized (the diagnosis time of respiratory system discomfort shall not exceed 10 days); 4. Women and their partners who have no planned pregnancy for nearly half a year and are willing to take effective contraceptive measures within 30 days from the first administration of the study drug to the last administration; 5. Agree not to participate in other clinical research within 30 days from the first administration of the study drug to the last administration; 6. Patients who voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. The pneumonia patients with severe new coronavirus infection met one of the following conditions: respiratory distress, RR 30 times / min; or SaO2 / SpO2 =C, AST > 5 times upper limit); 4. Patients with contraindications specified in the instructions of ritonavir tablets; 5. The patient who previous or ongoing use of protease inhibitors; 6. The pregnancy test of female subjects in the screening period was positive; 7. The researchers judged that it was not suitable to participate in this clinical trial (for example, patients who may be transferred to another hospital during the study period; patients with multiple basic diseases, etc.).?
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of composite advers outcomes: SPO2, PaO2/FiO2 and respiratory rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical remission rate and time;novel coronavirus nucleic acid detection; | — |
Countries
China
Contacts
Public ContactYe Gu
Shenyang Sixth People's Hospital
Outcome results
None listed