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Efficacy and safety of lipoic acid injection in reducing the risk of progression in common patients with novel coronavirus pneumonia (COVID-19)

Efficacy and safety of lipoic acid injection in reducing the risk of progression in common patients with novel coronavirus pneumonia (COVID-19)

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030471
Enrollment
Unknown
Registered
2020-03-02
Start date
2020-03-02
Completion date
Unknown
Last updated
2020-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

Lipoic acid group:Routine Therapy and administration of Lipoic acid injection
Blank control group:Routine Therapy and administration of placebo

Sponsors

Maoming People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients aged from 18 to 75 years old; (2) Mild patients with confirmed COVID-19 according to the diagnostic criteria of "novel coronavirus Infection Diagnosis and Treatment Plan (Trial 6th Edition)" issued by the National Health and Safety Commission; (3) Patients and their families voluntarily participated in the study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Female patients during pregnancy or lactation; (2) Patients allergic to lipoic acid or similar drugs (B vitamins), previously intolerant to the recommended dose of lipoic acid; (3) Patients who are taking part in clinical trials of other drugs; (4) Patients are taking other foods or drugs with antioxidant effect, such as vitamin C, vitamin E, etc. (5) Patients with other serious diseases that may threaten life, such as cancer.

Design outcomes

Primary

MeasureTime frame
Progression rate from mild to critical/severe;

Secondary

MeasureTime frame
NEW Score;Hospital Stay;30-day all-cause mortality;Levels of Inflammatory Factors and Oxidative Stress Markersive Stress Markers;

Countries

China

Contacts

Public ContactChen Chunbo

Maoming People's Hospital

gghicu@163.com+86 13922745788

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026