Chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Zhongshan Hospital Affiliated Fudan University ; Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the western medicine diagnosis, classification, and stage diagnosis are included patients; 2. History of 1 to 3 acute exacerbations in the past 12 months; 3. Aged 40 to 80 years; 4. The syndrome differentiation of TCM belongs to the syndrome of deficiency of lung qi, deficiency of lung and spleen, deficiency of lung and kidney, and deficiency of both lung and kidney; 5. Voluntarily receive treatment and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the above-mentioned western medical diagnosis, staging diagnosis and traditional Chinese medicine diagnosis standards; 2. Examination confirms chronic cough caused by tuberculosis, fungi, tumors, irritating gas allergies and other factors; 3. Patients with other respiratory diseases that can cause asthma or dyspnea; 4. pregnant or lactating women, allergic to Symbio 9ug / 320ug and Dongtian Changchun cream; 5. Patients with severe primary diseases such as cardiovascular, liver, kidney and hematopoietic system, and mental illness; 6. Concurrent severe heart dysfunction; 7. Contains factors that affect the observation of efficacy; 8. Those who do not meet the inclusion criteria, fail to use the drug as prescribed, cannot determine the efficacy or incomplete data, etc., which affect the efficacy or safety judgment; 9. Those who are participating in other clinical trials within 1 month before enrollment; 10. Patients with diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of acute attacks;TCM Syndrome Effect;SGRQ; | — |
Secondary
| Measure | Time frame |
|---|---|
| pulmonary function;6MWT;mMRC;Single-cell gene sequencing and mass spectrometry examination; | — |
Countries
China
Contacts
Public ContactZHANG WEI
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed