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HPV DNA, E6/E7 mRNA expression, and p16INK4A immunohistochemistry in patients with nasopharyngeal cancer and other head and neck cancers: a retrospective study in China

HPV DNA, E6/E7 mRNA expression, and p16INK4A immunohistochemistry in patients with nasopharyngeal cancer and other head and neck cancers: a retrospective study in China

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000030447
Enrollment
Unknown
Registered
2020-03-02
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nasopharyngeal cancer

Interventions

case series:no intervention

Sponsors

School of Public Health (Shenzhen), Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Individuals aged 18 years and above; 2. Only newly diagnosed cancer cases; 3. Patients with nasopharyngeal cancer and other head and neck cancers previously treated at SYSUCC, will be recruited; 4. Diagnosis of nasopharyngeal cancer and other head and neck cancers will be based on the International Classification of Diseases 10th Revision (ICD-10); 5. SCCs arise in the squamous epithelium of oral cavity, oropharynx, larynx, hypopharynx, nasopharynx, anal canal, perianal, and penile.

Exclusion criteria

Exclusion criteria: Maxilla, mandible, other bone, and cheek non-mucosal sites will be excluded.

Design outcomes

Primary

MeasureTime frame
HPV prevalence;—

Secondary

MeasureTime frame
P16 positive rate;—

Countries

China

Contacts

Public ContactHuachun Zou

School of Public Health (Shenzhen), Sun Yat-sen University

zouhuachun@mail.sysu.edu.cn+86 13926420419

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026