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Efficacy of aspirin and clopidogrel combined with Butylphthalide on frequent transient ischemic attack of atherosclerotic origin with ABCD2

Efficacy of aspirin and clopidogrel combined with Butylphthalide on frequent transient ischemic attack of atherosclerotic origin with ABCD2

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030423
Enrollment
Unknown
Registered
2020-03-01
Start date
2020-03-15
Completion date
Unknown
Last updated
2020-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transient ischemic attack

Interventions

Control group:aspirin and clopidogrel combined with placebo

Sponsors

Heze Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. With transient ischemic attack (TIA): a transient episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischemia, without acute infarction. 2. Patients with three or more attacks in the last 24 hours.

Exclusion criteria

Exclusion criteria: 1. Head CT or MRI plain scan found intracranial hemorrhage,aneurysm or other neurological symptoms which cannot accept the treatment; 2. Thrombolysis,anticoagulation therapy,carotid or cerebral or coronary artery stent implantation or reconstruction in Plan; 3. Being allergic to NBP, clopidogrel and aspirin; 4. With a history of ventricular aneurysm,atrial fibrillation or suspected cardiovascular embolism causing TIA; 5. Patients having taken NSAIDS for more than 7 days recently; 6. With a history of gastrointestinal bleeding within 6 months; 7. With a history of a major surgery within 30 days; 8. With coagulation dysfunction; 9. With previous history of non-traumatic intracranial hemorrhage; 10. With severe liver and kidney dysfunction; 11. Pregnancy or lactation; 12. Patients who do not understand or cooperate with the study, treatment or follow-up. Additionally, standard treatments such as hypoglycemic and antihypertensive therapy may be prescribed to all patients at the discretion of the investigators and clinicians.

Design outcomes

Primary

MeasureTime frame
a compound event of Stroke, TIA, ACS or death on days 7 and 90;

Countries

China

Contacts

Public ContactChen Yankun

Heze Municipal Hospital

kundan@126.com+86 18853054120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026