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Efficacy and safety of Xue-Bi-Jing injection in the treatment of severe cases of novel coronavirus pneumonia (COVID-19)

Efficacy and safety of Xue-Bi-Jing injection in the treatment of severe cases of novel coronavirus pneumonia (COVID-19)

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030388
Enrollment
Unknown
Registered
2020-03-01
Start date
2020-02-18
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel coronavirus pneumonia (COVID-19)

Interventions

Experimental group:On the basis of routine treatment, add 100ml of normal saline and 50ml of Xuebijing injection twice a day
Control group:conventional therapy

Sponsors

Jingzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The patient signs the written informed consent; 2. Aged 18-80 years; 3. the novel coronavirus novel coronavirus infection diagnostic criteria for pneumonia, namely, the new coronavirus pneumonia diagnosis and treatment plan (trial version sixth). It conforms to any of the following: 1) in case of shortness of breath, RR >= 30 times / min; 2) in case of resting state, oxygen saturation 50% should be treated as severe management; 4. The course of disease is within 14 days after onset.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to Xuebijing injection and its components; 2. Pregnant or lactating women; 3. Serious basic diseases affecting survival, including: malignant tumor, hematopathy, HIV, etc; 4. Expected death within 48 hours; 5. Patients who are participating in other clinical trials; 6. The researchers think other reasons are not suitable for clinical trials.

Design outcomes

Primary

MeasureTime frame
The percentage of patients who convert to moderate one;The rate of shock;Endotracheal intubation ratio;Time spent on the ventilator;mortality;Time of virus nucleic acid test turning negative;

Secondary

MeasureTime frame
CRP;IL-6;TNF-a;Time of improvement of clinical symptoms (fever, cough);Adverse drug reactions;white blood cell;lymphocyte;IL-8;length of stay in ICU;average length of hospitalization;

Countries

China

Contacts

Public Contactxiao wei

Jingzhou First People's Hospital

99xw@sina.com+86 071 68494565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026