mediastinal lesion
Conditions
Interventions
TBNA, 
TBCB 
and 
TBFB 
ultrasound 
guidance.
2.Group 
2: 
Gold Standard:Transbronchial needle aspiration and transbronchial forceps biopsy guided by endobronchial ultrasound.
Index test:1.Group 
Sponsors
Xinqiao Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged >= 15 years; 2. Patients with at least one mediastinal lesion with short-axis >= 1 cm that is detected by thoracic image; 3. Patients with recently discovered mediastinal lesions, clinical respiratory symptoms of cough, expectoration, thoracalgia, apnea, or complicated lung lesions implicated by thoracic image, which indicates the need of biopsy to identify the etiology; 4. Patients should have undergone necessary preoperative laboratory examinations and other examinations such as cardiac ultrasound or CTA when necessary, in order to exclude potential contradictions; 5. Patients are informed and the consent form are acquired.
Exclusion criteria
Exclusion criteria: 1.Patients with contradictions to endoscopic examination, such as severe cardiopulmonary diseases, coagulation disorders, intolerance to anesthesia or endoscopic operation, psychiatric disorders, or severe neurosis, and so on; 2.The EBUS procedure fails to detect the mediastinal lesion; 3.The mediastinal lesions are actually cysts or abscess; 4.Patients could not provide full informed consentsuch as with severe neurosis or mental diseases; 5.Patients need for additional procedures other than EBUS examination (such asendobronchial biopsy); 6.Patients have been previously randomised to an arm of the present trial or involved in other clinical trials in the recent 3 months; 7.Patients have any other conditions that are considered to be inappropriate to be involved in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diagnostic yield;diagnostic safety; | — |
Countries
Germany
Contacts
Public Contact??
Xinqiao Hospital
Outcome results
None listed