Systemic Sclerosis
Conditions
Interventions
Sponsors
The First Affiliated Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years, gender unlimited. 2. Signed the informed consent before the test. 3, The patients diagnosed as SSc by satisfying 2013 ACR classification criteria for SSc. 4. TSS15 >= 15; 5. Medsger severity score >= 2; 6. Prednisone dose<10mg/d and the dose has maintained for over 30 days.
Exclusion criteria
Exclusion criteria: 1. The patients who use CYC,MMF,FK506, CsA,LEF,glucocorticoids(>0.8mg/Kg*d),IVIG or plasma exchange within 30 days before the test,will be excluded. 2. Patients with malignant tumor, immune deficiency, uncontrolled severe infection or active peptic ulcer. 3. Pregnant women,lactating women and men or women with family planning in the next 12 months. 4. Patients with a history of allergy to the test drug. 5. Patients with active hepatitis or a history of serious liver disease. 6. Patients with serious heart, liver, kidney or other important organs lesions. 7. Patients whom the researchers don't think suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Medsger Severity Score; | — |
Countries
China
Contacts
Public ContactPingting Yang
The First Affiliated Hospital of China Medical University
Outcome results
None listed