Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Monitor cases, suspected cases and diagnosed cases:No
Sponsors
Tongji Hospital, Tongji Medical College, Huazhong University of science and technology
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: This study intends to select surveillance cases, suspected cases, and diagnosed cases of COVID-19 for children aged 0-18 who were admitted to the Department of Pediatrics, Tongji Hospital from December 2019 to June 2020. 1. Epidemiological classification: All Participants divided into three levels: high, medium and low risk according to the epidemiological history: (1) high risk: the participants are close to suspected or confirmed cases of COVID-19 within 14 days before the onset of illness; (2) medium risk: cluster cases of COVID-19 in the residence or community; (3) low risk: the residence or community has no cluster cases or not from epidemic place; 2. Monitoring cases: high-risk children with no symptom and medium-risk or low-risk children with the following symptoms: (1) Fever; (2) respiratory symptoms or weakness, nausea, vomiting, abdominal discomfort and diarrhea; 3. Suspected cases: If the high-risk children meet any 2 of the following 3 conditions, they are suspected cases. Any 2 of the following 3 surveillance cases in medium and low risk were suspected cases after elimination of influenza (no effect of oseltamivir phosphate for 2 days) and other common respiratory pathogenic infections: (1) Persistent fever, obvious respiratory symptoms, shortness of breath, pulse oxygen saturation decreased, or gastrointestinal symptoms such as nausea, vomiting, abdominal discomfort and diarrhea; (2) laboratory tests: white blood cells level normal or decreased , lymphocyte count decreased, CRP normal or slightly elevated; (3) chest radiology shows signs of COVID-19; 4. Diagnosed cases: all suspected cases who respiratory swabs or secretions, blood, feces and urine SARS-CoV-2 nucleic acid test is positive; viral gene sequencing is highly homologous with SARS-CoV -2.
Exclusion criteria
Exclusion criteria: (1) Exclude influenza virus, parainfluenza virus, adenovirus, respiratory syncytial virus,rhinovirus, human metapneumovirus, boca virus, and other known viral respiratory infections; (2) Exclude pneumonia caused by atypical microorganisms such as mycoplasma pneumoniae and legionella,bacterial pneumonia, fungal pneumonia, and tuberculosis; (3) Exclude children with basic diseases who have invasive fungal infections; (4) Exclude children with no clear infectious etiology, who have non-infectious diseases such as vasculitis, dermatomyositis, idiopathic interstitial lung disease, and organizing pneumonia; (5) The guardian does not agree to sign the informed consent or collect information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epidemiological characteristics;clinical features;Treatment outcome; | — |
Countries
China
Contacts
Public ContactYan Hao; Xiaoping Luo
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed