Gut-derived short-chain fatty acids improve cytokine storm in patients with ARDS through lung-gut axis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000030321

Enrollment

Unknown

Registered

2020-02-28

Start date

2020-03-01

Completion date

Unknown

Last updated

2020-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome

Interventions

experimental group:Probiotics

control group:placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All adult patients (aged >= 18 years); 2. With a diagnosis of ARDS; 3. Patients voluntarily participate in the experiment.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Expected to die within 48 hours; 3. Had a history of immune disease or long-term admission of immunosuppressive drug; 4. Patients with cardiogenic pulmonary edema.

Design outcomes

Primary

Measure	Time frame
IL-6;TNF-a;IL-1ß;sIgA;	—

Secondary

Measure	Time frame
Oxygenation index;Mechanical ventilation time;	—

Countries

China

Contacts

Public ContactYin Jiangtao

Affiliated Hospital of Jiangsu University

doctoryjt2438@163.com+86 13952943135

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026