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Clinical trial of TACE with oxaliplatin regimen in continuous hepatic artery chemotherapy combined with sorafenib in the treatment of intermediate and advanced primary liver cancer

Clinical trial of TACE with oxaliplatin regimen in continuous hepatic artery chemotherapy combined with sorafenib in the treatment of intermediate and advanced primary liver cancer

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030303
Enrollment
Unknown
Registered
2020-02-28
Start date
2012-02-01
Completion date
Unknown
Last updated
2020-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary liver cancer

Interventions

Case series:TACE+HAIC+sorafenib

Sponsors

Beijing Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) aged 18-75 years; (2) Eastern Cooperative Oncology Group (ECOG) performance status of 0-2; (3) Child-Pugh class A or B; (4) one HCC intermediate and advanced; (5) white blood cell counts >3x10^9/L and neutrophil counts >1.5x10^9/L; (6) serum creatinine 45%.

Exclusion criteria

Exclusion criteria: (1) currently had other malignancies; (2) uncontrollable infections (>2 grade infections; infections requiring antibiotic, antifungal, or antiviral interventions; infections requiring radiological or surgical interventions; infections with life-threatening consequences; or infections requiring urgent interventions); (3) pregnancy or breastfeeding; (4) previous sorafenib treatment; (5) severe allergies to contrast agents or other drugs.

Design outcomes

Primary

MeasureTime frame
overall survival;

Countries

China

Contacts

Public ContactXu Zhu

Peking University Cancer Hospital

drzhuxu@163.com+86 010 88196330

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026