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The research on salivary microbial community in the different stages of HIV infected patients.

The research on salivary microbial community in the different stages of HIV infected patients.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000030301
Enrollment
Unknown
Registered
2020-02-28
Start date
2018-01-01
Completion date
Unknown
Last updated
2020-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired Immune Deficiency Syndrome

Interventions

Case series:Subjects avoided eating, drinking, and brushing their teeth 1 hour before saliva collection

Sponsors

Beijing You'an Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: According to the United States CDC's staging criteria for infection case monitoring, HIV-infected patients were collected from the Department of Infectious Diseases, Beijing You'an Hospital, Capital Medical University: 10 cases of HIV-infected patients who did not receive HAART treatment in stages 0, 1, 2, 3; example. The basic information of clinical oral examination was collected, and the patient signed the agreement and passed the ethics committee review. Inclusion criteria for healthy controls: (1) Above 18 years old; (2) No lesions or damages in the oral mucosa; (3) Whole body healthy HIV antibody negative volunteers. Inclusion criteria for HIV-infected patients: (1) The clinical confirmation test is positive for HIV antibody test; (2) Above 18 years old; (3) No lesion or damage in the oral mucosa; (4) HIV-positive patients with stage 0, 1, 2, and 3 did not receive any treatment.

Exclusion criteria

Exclusion criteria: (1) Periodontal pockets >=4 mm, untreated cavity caries, oral abscesses, and missing teeth caused by various reasons for more than 8 teeth; (2) Those with mucosal lesions or damage in the oral cavity; (3) Those who have received HAART or other treatments; (4) have used glucocorticoids, immunosuppressants and antibiotics within 3 months; (5) have systemic diseases such as heart, liver, kidney, lung, diabetes, hypertension, and other immune system diseases; (6) Other patients with tumor and mental illness; (7) Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
saliva;blood viral load;CD4 counts;

Countries

China

Contacts

Public ContactYing Guo

Beijing You'an Hospital, Capital Medical University

153505774@qq.com+86 18515687688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026