Clinical observation for single intravenous preinjection of ketorolac tromethamine to inhibit cough caused by sufentanil during induction of general anesthesia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000030287

Enrollment

Unknown

Registered

2020-02-27

Start date

2020-02-29

Completion date

Unknown

Last updated

2020-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough caused by sufentanil during general anesthesia induction

Interventions

control group:Normal saline

experimental group:Intravenous injection of 0.5mg ketorolac tromethamine before anesthesia

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18~65 years old; 2. BMI: 18~30kg/m2; 3. ASA I~II grade; 4. Patients to be operataed on elective general anesthesia surgery.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or lactation women; 2. With a history of drug allergy; 3. With cognitive or mental illness; 4. With severe cardiovascular and cerebrovascular diseases, liver, kidney and hematopoietic diseases; 5. Long-term use of analgesics or hormones, drug abuse History; 6. Those who participated in other clinical trials or researchers considered inappropriate to participate in this experiment.

Design outcomes

Primary

Measure	Time frame
Coughing times;	—

Secondary

Measure	Time frame
Mean arterial pressure;Heart rate;pulse oxygen saturation;Dosage of anesthetic drug;Side effects of anesthesia during resuscitation;	—

Countries

China

Contacts

Public ContactTian Zhen

Suqian People's Hospital of Nanjing Drum-Tower Hospital Group

tianzhen1000@126.com+86 15261204303

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026