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Effects of ultrasound-guided stellate ganglion block combined with Pecs block on perioperative stress and inflammation response in patients undergoing breast cancer surgery

Effects of ultrasound-guided stellate ganglion block combined with Pecs block on perioperative stress and inflammation response in patients undergoing breast cancer surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030285
Enrollment
Unknown
Registered
2020-02-27
Start date
2020-02-21
Completion date
Unknown
Last updated
2020-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

control group:stellate ganglion block and pectoral space block with normal saline
experimental group 1:stellate ganglion block and pectoral space block with ropivacaine
experimental group 2:stellate ganglion block with ropivacaine
experimental group 3:pectoral space block with ropivacaine

Sponsors

Jiangyin Hospital Affiliated to Southeast University Medical School
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1) Aged 30-70 years; 2) ASA I-II; 3) Adult female patients undergoing radical mastectomy.

Exclusion criteria

Exclusion criteria: 1) infection at injection site; 2) liver and kidney dysfunction; 3) coagulation dysfunction; 4) arrhythmia; 5) mental disorder; 6) thyroid dysfunction; 7) severe cardiopulmonary dysfunction; 8) autonomic or central nervous system dysfunction; 9) history of couplant allergy; 10) distant metastasis of cancer cells; 11) patients with immune diseases; 12) patients who have received radiotherapy and chemotherapy; 13) patients who have received long-term oral sedatives.

Design outcomes

Primary

MeasureTime frame
IL-6;IL-8;TNF-a;cortisone;blood glucose;

Secondary

MeasureTime frame
HR;BP;SpO2;VAS;Ramsay score;complications;sleep quality;PACU stay time;length of hospital stay;

Countries

china

Contacts

Public ContactJun Geng

Jiangyin Hospital Affiliated to Southeast University Medical School

alinaglz@163.com+86 18861667601

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026