transient ischemic attack
Conditions
Interventions
Control group:Aspirin and clopidogrel combined with Butylphthalide placebo
Sponsors
Heze municipal hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Transient ischemic attack (TIA): a transient episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischemia, without acute infarction.
Exclusion criteria
Exclusion criteria: 1. Head CT or MRI plain scan found intracranial hemorrhage,aneurysm or other neurological symptoms which cannot accept the treatment; 2. Thrombolysis,anticoagulation therapy,carotid or cerebral or coronary artery stent implantation or reconstruction in Plan; 3. Being allergic to NBP, clopidogrel and aspirin; 4. A history of ventricular aneurysm,atrial fibrillation or suspected cardiovascular embolism causing TIA; 5. Take in NSAIDS for more than 7 days recently; 6. A history of gastrointestinal bleeding within 6 months; 7. A history of a major surgery within 30 days; 8. Coagulation dysfunction; 9. Previous history of non-traumatic intracranial hemorrhage; 10. Severe liver and kidney dysfunction; 11. Pregnancy or lactation; 12. Incomprehension or incooperation with the study or treatment or follow-up. Additionally, standard treatments such as hypoglycemic and antihypertensive therapy may be prescribed to all patients at the discretion of the investigators and clinicians.Previous studies indicated that 90% of strokes occurred in the layer with ABCD2>=4, so all the patients were divided into the low-risk layer and the medium-high-risk layer by the ABCD2 scale.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a compound event of Stroke, TIA, ACS or death on days 7 and 90; | — |
Countries
China
Contacts
Public ContactChen Yankun
Heze municipal hospital
Outcome results
None listed