Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
1 the critical group :injecting Mesenchymal stem cells
2 the severe group:injecting Mesenchymal stem cells
3 the control group of the critical group:injecting normal saline
4 the control group of the severe group:injecting normal saline
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Female patients aged >=18 years who were of childbearing years were excluded from pregnancy and agreed to use non-drug contraceptive measures during the study period; 2. SARS-CoV-2 nucleic acid test positive; 3. Lung CT examination showed evaluable lesions; 4. Meet the diagnostic criteria for severe or critical illness in the diagnosis and treatment program for new coronavirus pneumonia (trial version 6); 5. Subjects voluntarily participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to drugs and excipients used in this study; 2. Pregnant and lactating women and women of child-bearing years did not agree to use contraception during the experiment; 3.Have malignant tumor or hypercoagulant state; 4. Suffer from mental illness and can't cooperate well; 5. Those who have participated in or are participating in clinical trials of other drugs during the course of the disease; 6. Other conditions considered inappropriate for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SP02;lesions of lung CT;temperature;Blood routine;Inflammatory biomarkers; | — |
Secondary
| Measure | Time frame |
|---|---|
| hepatic and renal function; | — |
Countries
China
Contacts
Public ContactChengyun Liu
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed