the total knee arthroplasty
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who signed the informed consent; 2. aged 18-80 years; 3. ASA grade II~III; 4. intending to undergo knee replacement.
Exclusion criteria
Exclusion criteria: 1. allergy to the medicine of the study; 2. Contraindication (local anesthetic allergy, around puncture infection and blood coagulation disorder); 3. has a history of Analgesic dependence; 4. patients with dementia or severe cognitive dysfunction within 3 months; 5. any heart cerebrovascular accident occurred, such as stroke, transient ischemic attack (TIA), cardiac insufficiency, etc.; 6. any communication difficulty; 7. severe liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the highest pain scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| analgesic;postoperative delirium;The proportion of moderate to severe postoperative pain;Postoperative nausea and vomiting;the quality of life; | — |
Countries
China
Contacts
The First Affiliated Hospital of Anhui Medical University