A prospective non-randomized controlled clinical trial of transgastric gallbladder-preserving cholecystolithotomy via pure natural orifice transluminal endoscopic surgery

A prospective non-randomized controlled clinical trial of transgastric gallbladder-preserving cholecystolithotomy via pure natural orifice transluminal endoscopic surgery - NOTES

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000030152

Enrollment

Unknown

Registered

2020-02-24

Start date

2020-03-01

Completion date

Unknown

Last updated

2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gallbladder stone

Interventions

case group:Transgastric gallbladder-preserving cholecystolithotomy via pure natural orifice transluminal endoscopic surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The size of gallbladder is basically normal, the thickness of gallbladderwall is not more than 5 mm; 2. the function of gallbladder is normal; 3. No stone obstruction of cystic duct; 4. No more than 10 gallstones; 5. No acute attack of cholecystitis in the near future; 6. The patient has a clear requirement for gallbladder preservation and fully understands the possibility of stone recurrence; 7. Aged 18-65 years, no severe cardiopulmonary insufficiency and hepatorenal insufficiency, no history of taking anticoagulant drugs.

Exclusion criteria

Exclusion criteria: 1. Acute cholecystitis; 2. Gallbladder full of stones; 3. Gallbladder separation; 4. Atrophy of gallbladder; 5. Cholelithiasis or acute pancreatitis; 6. Suspected malignant tumor of gallbladder; 7. History of subtotal gastrectomy; 8. Serious diabetes mellitus; 9. Lactation or pregnancy.

Design outcomes

Primary

Measure	Time frame
Recurrence rate of gallstone;Contraction function of gallbladder;Mortality;Incidence of complications;	—

Secondary

Measure	Time frame
Gallbladder wall thickness; Incidence of of acute cholecystitis;Incidence of choledocholithiasis;Length of hospitalization;Cost in hospitalization;Transfer rate for surgical operation;Abdominal infection rate;Transfusion rate;Incidence of gallbladder bile leakage;Closure rate of gastric perforation;Operative time;	—

Countries

China

Contacts

Public ContactYang Gongli

Shenzhen University General Hospital

372073843@qq.com+86 13886827389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026