cardiopulmonary bypass in cardiac surgery
Conditions
Interventions
1:The skin of the patients’ forehead will be carefully cleaned with 70% isopropyl alcohol. After drying, electrodes for RE will be placed as follows in combination with the manufacturer’s recommendati
2:The skin of the patients’ forehead will be carefully cleaned with 70% isopropyl alcohol. After drying, electrodes for SE will be placed as follows in combination with the manufacturer’s recommendati
3:The skin of the patients’ forehead will be carefully cleaned with 70% isopropyl alcohol. After drying, electrodes for Bis will be placed as follows in combination with the manufacturer’s recommendat
Sponsors
The First Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Participants undergoing elective cardiac surgery with hypothermic CPB; 2. Acknowledgement and acceptance of written informed consent; 3. Aged between 16 and 60 years and an ASA score of II-III; 4. Body weight > 50 kg and body mass index between 18 and 24 kg/m2; 5. CPB with an estimated duration of at least two hours.
Exclusion criteria
Exclusion criteria: 1. Pre-existing psychiatric or neurologic disorders; 2. History of major trauma to the head; 3. Long-term drug abuse; 4. Medication affecting the central nervous system; 5. Congenital or acquired scalp or skull abnormalities; 6. Patients participating in other clinical trials; 7. Pre-operative platelet counting < 100 x 109, platelet insufficiency, or coagulopathy; 8. Hepatic or renal dysfunction; 9. Hypoproteinemia (total protein < 60 g); 10. Allergic reaction to anesthetic drugs; 11. Women who are pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RE;SE;the Bis;the nasopharyngeal temperature; | — |
Secondary
| Measure | Time frame |
|---|---|
| patient age; gender; height; weight; major pre-operative diagnosis; surgical name; the presence of hypertension or diabetes; a history of pre-operative myocardial infarction; cardiac ejection fraction; duration of CPB; and aortic clipping.;patient age; gender; height; weight; major pre-operative diagnosis; surgical name; the presence of hypertension or diabetes; a history of pre-operative myocardial infarction; cardiac ejection fraction; duration of CPB; and aortic clipping.; | — |
Countries
China
Contacts
Public ContactTian Ayong
The first hospital of China Medical University
Outcome results
None listed