Anesthesiology
Conditions
Interventions
experimental group:SPI monitoring
control group:MAP monitoring
Sponsors
The Fourth Affiliated Hospital, Zhejiang University, School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Line selection in our hospital 100 cases undergoing elective general anesthesia surgery patients, ranging in age from 18 to 60 years of age, and gender not limited, ASA class is I ~ II.
Exclusion criteria
Exclusion criteria: 1. Allergic to narcotic drugs;Abnormal coagulation function; 2. Patients with serious cardiorespiratory disorders (pacemaker implantation, atrial fibrillation); 3. Endocrine diseases (diabetes, abnormal thyroid function); 4. Peripheral neuropathy and peripheral coldness; 5. Liver and kidney disease; 6. Patients with neurological complications; 7. Opioid abuse or drug users; 8. Using drugs such as beta blocker or clonidine to affect autonomic nerve regulation; 9. Pregnant women;Patients with poor hypertension control (SBP >= 160mmHg and/or DBP >= 100mmHg); 10. Obese patients (BMI >= 30); 11. Lean patients (BMI < 18.5); 12. Transfer to open surgery or reoperation after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opioid dosages;Postoperative agitation, nausea and vomiting, NRS score, additional dose of analgesics, spontaneous breathing time, eye opening time, and extubation time were recorded in PACU.;Perioperative cortisol, il-6 and il-8 levels;The VAS score, the use of supplementary analgesics, the incidence of nausea and vomiting, pruritus, urinary retention, and the time of anal exhaust and feeding were observed within 3 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Propofol dosage, circulation status (blood pressure and heart rate); | — |
Countries
China
Contacts
Public ContactJian Guo
The Fourth Affiliated Hospital, Zhejiang University, School of Medicine
Outcome results
None listed