acute kidney injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with AKI and sepsis AKI in all ICUs of the study centers were included in the study, and the patients met all the following criteria: 1) Admission to ICU; 2) Aged > 18 years; 3) Meet the criteria for the diagnosis of AKI in the global kidney disease prognostic organization (KIDGO): within 48 hours the SCr rise >= 26.5µmol/L; or within 7 days the SCr rise >= 1.5 times the baseline value; or within 6 hours the urine volume = 2.
Exclusion criteria
Exclusion criteria: Exclusion criteria: Potential subjects who meet the entry criteria will be excluded if they meet any of the following criteria 1) pregnant and perinatal women; 2) In ICU for less than 24 hours; 3) having a history of organ transplantation; 4) Patients with had been renal replacement therapy; 5) Patients and their families cannot cooperate with the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Medical history (hypertension, diabetes, heart disease, liver disease, chronic kidney disease, malignant tumor);Surgery (surgery, bleeding, intraoperative hypotension);Surgical patients (total intraoperative intake/total output, crystal fluid, colloid fluid, blood products);vasoactive drug, nephrotoxic drug;Immediate testing into ICU: PO2/FIO2, lactic acid, HB, TBIL, TNI, BNP, etc.;28-day mortality, 90-day mortality, 1-year mortality, ICU time, hospitalization, cumulative mechanical ventilation;neutrophil gelatinase-associated lipocalin (NGAL), CMTM Family, cytokine-like 1, Lysozyme G-like 1; | — |
Countries
China
Contacts
Peking University People's Hospital