Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Two groups:Different stem cell doses
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients are eligible for admission if they meet all of the following criteria within 5-7 days of their first ICU admission. 1) Aged 18-75 years; 2) The patient meets the ARDS diagnostic standard (Berlin standard) and needs intubation ventilator-assisted or ECMO-assisted treatment; 3) The primary disease caused by 2019-nCoV virus infection; 4) Imaging data suggest bilateral lung lesions; 5) Voluntarily participate in clinical research; fully understand, know, and sign informed consent.
Exclusion criteria
Exclusion criteria: 1) ARDS caused by other viral infections; 2) ARDS caused by other non-viral infections (such as trauma); 3) WHO grade III or IV pulmonary hypertension; 4) Patients with malignant tumors of the lungs and other systems; 5) Positive blood pregnancy test in lactating women or screening women; 6) Idiopathic IgA deficiency; 7) Cardio-cerebrovascular events in the near future (3 months); 8) patients with lung transplantation; 9) HIV positive patients; 10) Tester excluding from the investigator's judgment a history or current evidence of any disease, treatment, or laboratory abnormality that may confuse the results of the study, interfere with the participant's participation in the study process, or are not in the best interest of the participant to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to leave ventilator on day 28 after receiving MSCs infusion; | — |
Countries
China
Contacts
Public ContactZhang Wei
The First Affiliated Hospital of Nanchang University
Outcome results
None listed