Aortic Dissection
Conditions
Interventions
Case series:autologous platelet separation versus
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patients voluntarily signed the informed consent form of the trial, with good compliance and follow-up; 2. The patients with diagnosis of aortic dissection who undergoing aortic dissection surgery cardiopulmonary bypass; 3. Male and female patients aged 18-75 years and whose weight is more than 50kg; 4. Before the operation, the number of platelets in patients was not lower than the normal range, and the hematocrit (HCT) was more than 35%.
Exclusion criteria
Exclusion criteria: 1. Those who refuse to sign informed consent. 2. Patients with platelet count less than 50x10^9/L, hypoproteinemia and coagulation mechanism disorders; 3. Patients with platelet disease before operation and those who are not suitable for collection during emergency operation; 4. Systemic bacteremia and sepsis; 5. Aspirin, clopidogrel and other antiplatelet drugs were used within 72 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| perioperative autologous and allogeneic blood transfusion volume;Changes of hemoglobin, platelet count, prothrombin time, APTT and thromboelastogram in perioperative period;postoperative drainage, complications, ICU stay time,hospital mortality, 3-year survival rate, length of hospitalization, Cost of transfusion and hospitalization;perioperative indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| general condition of patients; | — |
Countries
China
Contacts
Public ContactXianjun Ma
Qilu Hospital of Shandong University
Outcome results
None listed