Preoperative Ultra-Short-Course Chemotherapy Combined with Simple Surgery Treated Chest Wall Tuberculosis: a Randomized Controlled Trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000030105

Enrollment

Unknown

Registered

2020-02-23

Start date

2020-03-01

Completion date

Unknown

Last updated

2020-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chest Wall Tuberculosis

Interventions

1-7 days group:Preoperative 1-7 days chemotherapy combined with surgery

7-14 days group:Preoperative 7-14 days chemotherapy combined with surgery

14-21 days group:Preoperative 14-21 days chemotherapy combined with surgery

21-28 days group:Preoperative 21-28 days chemotherapy combined with surgery

>28 days group:Preoperative >28 days chemotherapy combined with surgery

Eligibility

Sex/Gender

All

Age

5 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Simple chest wall tuberculosis was diagnosed according to symptoms, physical signs, imaging examination results, and etiological and histopathological results. 2. Patients are evaluated and were found to be appropriate candidates for surgical focus debridement for tuberculosis.

Exclusion criteria

Exclusion criteria: 1. Contraindications to surgery are noted. 2. Lost to follow-up. 3. No compliant with the recommended chemotherapy treatment.

Design outcomes

Primary

Measure	Time frame
Cure rate;Recurrence rate;Rifampicin concentrations in different tissues;	—

Countries

China

Contacts

Public ContactWeidong Zhang

Henan Provincial Chest Hospital

zhangweidong0371@126.com+86 18239975267

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026