Cholelithiasis with choledocholithiasis
Conditions
Interventions
experimental group:Intraoperative incision infiltration analgesia combined with timing intravenous injection of selective COX 2 inhibitor
control group:Intraoperative incision infiltration and postoperative continuous intravenous injection of opioids for analgesia
Sponsors
Xuanwu Hospital of Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients with cholelithiasis and choledocholithiasis were treated by laparoscopic cholecystectomy combined with choledochoscopy and choledocholithotomy (primary suture or T-tube drainage). (2) 18-80 years old, mental health, intelligence level can correctly complete the pain scale evaluation. (3) We agreed and signed the operation informed consent and anesthesia analgesia informed consent, and accepted the multimodal postoperative pain relief program determined by random grouping.
Exclusion criteria
Exclusion criteria: (1) Due to the unexpected condition, the patient can not complete the established pain relief program, stop or change the established pain relief program. In case of serious operation related complications leading to death and unplanned reoperation. (2) The patients were diagnosed as malignant tumor during and after operation. (3) Patients with hepatolithiasis. (4) Patients who had ERCP and EST before. (5) Secondary acute severe biliary pancreatitis. (6) Conversion to open surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative nausea;Postoperative vomiting;Postoperative dizziness;Recovery time of postoperative peristalsis;Time of landing after operation;Cost of analgesic treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative analgesic effect; | — |
Countries
China
Contacts
Public ContactZheng Yamin
Xuanwu Hospital of Capital Medical University
Outcome results
None listed