Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
control group with common NCP:conventional treatment
experimental group with common NCP:conventional treatment combined with ozone therapy
experimental group with severe NCP:conventional treatment combined with ozone therapy
control group with severe NCP:conventional treatment
experimental group with critical NCP:conventional treatment combined with ozone therapy
control group with critical NCP:conventional treatment
Sponsors
Tianjin Huanhu Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years; 2. Within 1 week of onset; 3. Meet the diagnostic criteria of common, severe and critical NCP, according to "Pneumonitis Diagnosis and Treatment Scheme for Novel Coronavirus Pneumonia (Trial Version 6)". 4. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Any situation that does not allow the program to proceed safely; 2. The patient may be transferred to a non-participating hospital within 72 hours; 3. Those who have continued to use immunosuppressive agents or organ transplants for the past 6 months; 4. Glucose-6-phosphate dehydrogenation Enzyme deficiency (faba bean disease) 5; 5. Patients treated with any of the antiviral drugs listed in the protocol during hospitalization before enrollment; 6. Those participating in other clinical trials. 7. Those who are allergic to ozone or hypersensitive.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chest imaging;RNA test of COVID-19;Time to remission/disappearance of primary symptoms: defined as the number of days when the three main symptoms of fever, cough, and shortness of breath are all relieved / disappeared;Completely antipyretic time: completely antipyretic was defined as the body temperature return to normal for over 24 hours.;Blood oxygen saturation;Time to 2019-nCoV RT-PCR negativity: defined as the last test time for two consecutive negative respiratory viral nucleic acid tests (sampling interval of at least 1 day);Liver, renal and heart function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Conversion of severe cases: defined as the number of severe and critical cases that occurred after the study was included and the intervention was initiated;Incidence of medical complications during hospitalization: defined as medical complications during pneumonia isolation hospitalization due to novel coronavirus infection, including combined bacterial infections, exacerbation of underlying diseases, etc.;Routine blood test;C-reactive protein;Blood gas analysis; | — |
Countries
China
Contacts
Public ContactXiaoguang Tong
Tianjin Huanhu Hospital
Outcome results
None listed