Alzheimer's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Gender is not limited, 50 <= age <= 85; 2. Patients are diagnosed with Alzheimer's disease; 3. Patients with Alzheimer's disease assessed by clinical dementia scale (CDR); 4. Patients with Alzheimer's disease who were stable and did not change the drug with in 4 weeks; 5. Patients with Alzheimer's disease who have a trusted guardian to accompany and assist in participation; 6. Patients with Alzheimer's disease and their families agreed to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Have MRI, electrophysiological examination (history of seizures or family history of epilepsy, VP shunt in the body, metal implants including implants, skull defects, etc.); 2. Combined with serious underlying diseases such as cardiovascular disease, rheumatic immune diseases, etc.; 3. Disorder of consciousness; 4. There have been strokes, head injury or other neuropsychiatric diseases; 5. The patient is unwilling or unable to cooperate with the test and cannot complete the test; 6. Other researchers judged that they could not participate in the study; 7. Participate in other clinical trials during the same period; 8. Patients with spontaneous bleeding tendency or bleeding after injury (thrombocytopenic purpura, leukemia, hemophilia, etc.) and local skin infections should not be treated with acupuncture; 9. Patients with a history of using drugs, alcohol or sedatives.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alzheimer's Disease Assessment Scale-Cognitive section;Amplitude of Low-Frequency Fluctuation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quantitative Dectroencephalography;Neuropsychiatric Inventory;Pittsburg Sleep Quality Index Scale;Activity of Daily Living; | — |
Countries
China
Contacts
Huashan Hospital Fudan University