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Study on the mechanism and effect of acupuncture on Alzheimer's disease based on magnetic resonance imaging and electroencephalography

Study on the mechanism and effect of acupuncture on Alzheimer's disease based on magnetic resonance imaging and electroencephalography

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030100
Enrollment
Unknown
Registered
2020-02-23
Start date
2020-02-10
Completion date
Unknown
Last updated
2020-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease

Interventions

experimental group:acupuncture

Sponsors

Huashan Hospital Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Gender is not limited, 50 <= age <= 85; 2. Patients are diagnosed with Alzheimer's disease; 3. Patients with Alzheimer's disease assessed by clinical dementia scale (CDR); 4. Patients with Alzheimer's disease who were stable and did not change the drug with in 4 weeks; 5. Patients with Alzheimer's disease who have a trusted guardian to accompany and assist in participation; 6. Patients with Alzheimer's disease and their families agreed to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Have MRI, electrophysiological examination (history of seizures or family history of epilepsy, VP shunt in the body, metal implants including implants, skull defects, etc.); 2. Combined with serious underlying diseases such as cardiovascular disease, rheumatic immune diseases, etc.; 3. Disorder of consciousness; 4. There have been strokes, head injury or other neuropsychiatric diseases; 5. The patient is unwilling or unable to cooperate with the test and cannot complete the test; 6. Other researchers judged that they could not participate in the study; 7. Participate in other clinical trials during the same period; 8. Patients with spontaneous bleeding tendency or bleeding after injury (thrombocytopenic purpura, leukemia, hemophilia, etc.) and local skin infections should not be treated with acupuncture; 9. Patients with a history of using drugs, alcohol or sedatives.

Design outcomes

Primary

MeasureTime frame
Alzheimer's Disease Assessment Scale-Cognitive section;Amplitude of Low-Frequency Fluctuation;

Secondary

MeasureTime frame
Quantitative Dectroencephalography;Neuropsychiatric Inventory;Pittsburg Sleep Quality Index Scale;Activity of Daily Living;

Countries

China

Contacts

Public ContactWang Nianhong

Huashan Hospital Fudan University

wnh2005@126.com+86 13761352781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026