Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Experimental group:Iv injection of Wharton's Jelly mesenchymal stem cells (1×10^6/kg), cell suspension volume: 40ml
Control group:Iv 40ml saline
Sponsors
The Sixth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) age 18-80 years old, regardless of gender: 2) the diagnosis criteria of severe nCoV pneumonia in line with the 6th edition of China's new coronavirus pneumonia diagnosis scheme: a.B. Real-time fluorescence rt-pcr of respiratory tract specimens or blood samples was used to detect positive nCoV nucleic acid;3) critical cases of nCoV pneumonia: meet one of the following criteria: a. respiratory failure and mechanical ventilation required;B. shock;C. Combined with other organ failure, intensive care unit is required;4) patients with poor treatment response: that is, the above critically ill patients have undergone active modern medicine to fight against shock, correct acidosis, improve multi-organ function rescue and ECMO assisted breathing, and have not been improved by circulation assisted treatment and hormone application;5) those who signed the informed consent and agreed to participate in the initial clinical trial were selected.
Exclusion criteria
Exclusion criteria: No
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The nucleic acid of the novel coronavirus is negative;CT scan of ground glass shadow disappeared; | — |
Countries
China
Contacts
Public ContactLianru Gao
The Sixth Medical Center of PLA General Hospital
Outcome results
None listed