Coronary heart disease
Conditions
Interventions
contrast group:no nerve block,postoperative PCVA
3/4 group:TTPB in the 3/4 intercostal space, the same PCVA as C group
4/5 group:TTPB in the 4/5 intercostal space, the same PCVA as C group
Sponsors
The First Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Preoperative color Doppler ultrasound: M-mode ultrasound Teichholz method to measure left ventricular ejection fraction >= 50%; 3. Elective open CABG surgery under CPB; 4. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Have contraindications to nerve block; 2. Have a history of cardiac surgery; 3. Need ventricular assist devices such as IABP to assist circulation before surgery; 4. Have a history of cardiac arrest; 5. Have cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative opioid consumption;Cool sansation block range;Range of decreased mechanical pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative mechanical ventilation time;ICU stay;Postoperative hospital stay;nausea and vomitting;Short-term myocardial injury markers after surgery;Heart rate (bpm) and blood pressure (mmHg) fluctuate to the maximum value during operative stimulation;Consumption of vasoactive agents or antihypertensive drugs intraoperatively;NRS pain score at 1.2.3.5.7 days after surgery; | — |
Countries
China
Contacts
Public ContactYu Chen
The First Affiliated Hospital affiliated to Sun Yat-Sen University
Outcome results
None listed