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A Prospective Observational Study to Investigate the Correlation Analysis Between Neonatal Hyperbilirubinemia and Deafness Gene

Correlation analysis between neonatal hyperbilirubinemia and deafness gene

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000030075
Enrollment
Unknown
Registered
2020-02-22
Start date
2020-03-01
Completion date
Unknown
Last updated
2020-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

deafness

Interventions

hearing impairment group vs non hearing impairment group:N/A

Sponsors

Xiamen Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Daily aged = 35 weeks, body weight >= 1.8kg, Apgar score of 1 minute, 5 minutes and 10 minutes after birth were all above > 7 points. The first diagnosis after admission was neonatal hyperbilirubinemia, which was mainly unassociated with elevated bilirubin. BAEP examination was completed within 48 hours after admission.

Exclusion criteria

Exclusion criteria: 1. family history of deafness; 2. history of birth anoxia, neonatal asphyxia; 3. malformed external auditory canal, abnormal middle ear function; 4. neonatal intracranial infection, intracranial hemorrhage, neonatal hypoxic-ischemic brain injury; 5. history of cytomegalovirus infection and fever infection during pregnancy, history of ototoxic drug application, and history of congenital neurological diseases of the mother; 6. Further exclude those with incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Listening data;deafness gene;

Countries

China

Contacts

Public ContactWu Xiaohui

Department of Otolaryngology-Head and Neck Surgery, Children’s Hospital of Fudan University; Xiamen Children's Hospital

alley-wu@163.com+86 13459292112

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 18, 2026