Lumbar fusion
Conditions
Interventions
experimental group:adjusted the target concentration of remifentanil according to the change of analgesic / anti injury index.
control group:adjusted the target concentration of remifentanil according to the change of hemodynamics.
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Aged >= 65 years old, ASA grade II~ III, body mass index (BMI): 18 ~ 30kg / m2, the first time to perform selective lumbar fusion under intravenous general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with poor blood glucose control (fasting blood glucose >= 7.0mmol/l); 2. Severe cardiopulmonary disease; 3. Liver and kidney dysfunction; 4. Patients with coagulation dysfunction; 5. Patients with previous history of mental illness and dementia who could not cooperate with the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of major postoperative complications in elderly patients (delirium, pulmonary infection, hypoxemia, wound infection, lower extremity deep vein thrombosis, etc.); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative outcome of elderly patients (exhaust, defecation, eating, intake time, landing time, discharge time);blood sugar;lactic acid;C-reactive protein;cortisol; | — |
Countries
China
Contacts
Public ContactWang Tianlong
Xuanwu Hospital Capital Medical University
Outcome results
None listed