prostate cancer
Conditions
Interventions
experimental group:MRI-TRUS software fusion was used to conduct perineal prostate puncture guided by experimental instruments
control group:MRI-TRUS cognitive fusion, ultrasound-guided transrectal puncture
Sponsors
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
Male
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: 1. Male, younger than 80 years old; 2. Meet any of the following criteria: 1) rectal examination (DRE) to find suspicious nodules of the prostate, any PSA value; 2) PSA>=10ug/L; 3) PSA 4ug/L to 10ug/L; f/t PSA= 2 points; 4. Prostate length <= 64mm; 5. Compliance is good and can communicate well with researchers; 6. Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with prostate cancer or acute prostatitis have been diagnosed; 2) In the acute infection period, or, urinary tract infection,investigator believe that abnormal urine routine has clinical significance ; 3)Prostate puncture within 1 month; 4) Being in a decompensated period of cardiac insufficiency; 5) Those who have a serious bleeding tendency, or those who take anticoagulants for a long time can not stop the drug; 6) have severe internal hemorrhoids, external hemorrhoids, perianal or rectal lesions; 7) Patients with severe bone and joint disease cannot be placed in the left lateral position or the lithotomy position; 8) Have a high blood pressure crisis; 9) unable to perform anesthesia; 10) Those who have mental illness or mental disorders who do not understand the informed consent form; 11) Other surgical contraindications, or those considered by the investigator to be unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive detection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Targeted puncture positive detection rate;Gleason>=7 detection rate;biospy time;blood;Postoperative FRS score;Ultrasonic image quality evaluation;Concordant rate of targeted puncture and MRI report;Device function evaluation; | — |
Countries
China
Contacts
Public ContactJian Huang
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Outcome results
None listed