Adversed thoracic aortic remodeling early after open surgery for Stanford A aortic dissection
Conditions
Interventions
experimental group:Endovascular repair
control group:No intervention
Sponsors
Department of Cardiovascular Surgery, West China Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) The patient is between 18 and 80 years old; 2) Patients who were diagnosed with type A aortic dissection within 0-90 days and received sun's surgery 30 days later; 3) The patient did not received endovascular repair; 4) Residual aortic dissection was found at the distal end of the elephant trunk stent, and the false lumen area of the thoracic descending aorta at the end of the stent was > 50% aortic cross section area; 5) The left subclavian artery has been reconstructed; 6) The life expectancy of patients is more than 12 months; 7) Patients can understand the purpose of the experiment, participate in it voluntarily and sign the informed consent; 8) Patients are willing to follow up for evaluation as required by the clinical trial protocol.
Exclusion criteria
Exclusion criteria: 1) Chronic aortic dissection; 2) Patients who do not have appropriate vascular access, are allergic to alloy materials, have severe renal insufficiency or may have a serious reaction to contrast agent and are not suitable for endovascular repair; 3) Myocardial infarction or cerebrovascular accident occurred within 1 month; 4) Patients whom the investigator deems inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All causes mortality;Reoperation intervention rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| diameter of true lumen (end of elephant trunk stent/diaphragm plane/lower plane of renal artery);diameter of false lumen (end of elephant trunk stent/diaphragm plane/lower plane of renal artery);volume of true lumen;volume of false lumen;Diameter of circular aorta (end of elephant trunk stent/diaphragm plane/lower plane of renal artery);Aortic growth rate;Major adverse cardiovascular events;Spinal cord ischemia;Acute kidney injury;Bowel ischemia;Dissection rupture;Stent graft-induced new entry;Degree of false lumen thrombosis; | — |
Countries
China
Contacts
Public ContactJia Hu
Department of Cardiovascular Surgery, West China Hospital, Sichuan University
Outcome results
None listed