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Effects of different initiation time of epidural labor analgesia on intrapartum fever

Effects of different initiation time of epidural labor analgesia on intrapartum fever

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000030047
Enrollment
Unknown
Registered
2020-02-21
Start date
2020-02-21
Completion date
Unknown
Last updated
2020-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

labor analgesia

Interventions

orifice of the uterus 2-3cm group:epidural labor analgesia
orifice of the uterus 3-4cm group:epidural labor analgesia
orifice of the uterus > 4 cm group:epidural labor analgesia

Sponsors

The First Affiliated Hospital of University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) Nulliparas; 2) with singleton cephalic presentation; 3) term pregnancy (more than 37 weeks); 4) with regular uterine contractions; 5) intent to receive epidural labor analgesia; 6)after the evaluation of anesthesia clinic; 7) signed the informed consent.

Exclusion criteria

Exclusion criteria: 1) Parturients who had a baseline temperature of 37.5 degrees C and above; 2) contraindications to intraspinal analgesia; 3)pregnancy-related complication such as diabetes mellitus or preeclampsia; 4) patients with active cardiac, pulmonary, neurologic disease ,metabolic disease; 5) patients who received medications known to affect body temperature (acetaminophen, ibuprofen or prostaglandin); 6) parturients who delivered within 2 hours or over 8 hours after analgesia and needed for cesarean delivery.

Design outcomes

Primary

MeasureTime frame
materna temperature;inflammatory cytokines;placental neutrophilic inflammation;

Secondary

MeasureTime frame
the use of analgesic;labor characteristics and events;neonatal Apgar score;infant outcome;

Countries

China

Contacts

Public ContactJia Yang

South District of the First Affiliated Hospital of University of Science and Technology of China

yangjiahao79@163.com+86 13965059649

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026