Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age 18-70 years (2) Clinical symptoms, signs, and lung CT suggest changes in lung inflammation. Patients diagnosed with new type of coronavirus pneumonia combined with more than one nucleic acid test (3) Clinical symptoms, signs, and lung CT suggest lung inflammation changes. Combined with more than one respiratory or blood specimen virus gene sequencing, it is highly homologous to known new coronaviruses. (4) Negative nucleic acid or viral gene test, but New Crown Pneumonia expert group discusses cases with high suspicion of New Crown Pneumonia (5) Voluntarily sign the informed consent and agree to comply with the requirements of the test protocol (6) Patients can communicate in words or words. Sign informed consent (7) The patient agrees and has the ability to complete auxiliary tests related to the trial
Exclusion criteria
Exclusion criteria: (1) Subject has a history of tumor (2) Female patients of childbearing age during pregnancy, lactation or recent birth planning (3) Highly allergic constitution or history of severe allergies (4) Coagulation disorders such as hemophilia (5) Those with positive serological tests such as AIDS, syphilis, etc. (6) Patients who have participated in or are participating in other drug trials within one month (7) Patients who the investigator refused to participate in this clinical trial (8) There is a large area of pulmonary vascular embolism and severe pulmonary hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coronavirus nucleic acid markers negative rate;Symptoms improved after 4 treatments;Inflammation (CT of the chest); | — |
Secondary
| Measure | Time frame |
|---|---|
| Trough and peak of pulmonary function FEV1;Lymphocyte subpopulation changes; | — |
Countries
China
Contacts
Second Hospital of University of South China, Hengyang