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Multicenter randomized controlled trial for rhG-CSF in the treatment of novel coronavirus pneumonia (COVID-19)

Multicenter randomized controlled trial for rhG-CSF in the treatment of novel coronavirus pneumonia (COVID-19)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000030007
Enrollment
Unknown
Registered
2020-02-19
Start date
2020-02-03
Completion date
Unknown
Last updated
2020-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

Experimental group:rhG-CSF, 5ug/kg, combinated with standard treatment
Control group:standard treatment

Sponsors

The First Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 15-80 years,diagnosed with mild, common, and severe novel coronavirus pneumonia in accordance with the diagnostic criteria for the diagnosis and treatment of novel coronavirus pneumonia issued by the National Health Commission (trial version 5); 2. White blood cell Count < 15.0 x 10^9/L and Lymphocyte Count < 0.8 x10^9/L.

Exclusion criteria

Exclusion criteria: 1. Combining basic diseases such as hypertension, diabetes, and coronary heart disease; 2. Malignant tumor or with a history of malignant tumor; 3. pregnant or lactating women; 4. suffer from severe mental illness; 5. History of unstable angina pectoris or myocardial infarction within 6 months; coronary angiography suggested severe stenosis of the main branches of the coronary arteries; 6. History of cerebral infarction or cerebral hemorrhage within 6 months; 7. People who are intolerant or allergic to rhG-CSF; 8. Patients were judged unsuitable for inclusion in the trial.

Design outcomes

Primary

MeasureTime frame
Clinical symptoms;Blood routine;the viral load of 2019-nCOV of throat swab;TBNK cell subsets;TH1/TH2 Cytokine;Chest CT;

Countries

China

Contacts

Public ContactNanshan Zhong

The First Affiliated Hospital of Guangzhou Medical University

linling@gird.cn+86 13902233092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026