pneumonitis caused by novel coronavirus
Conditions
Interventions
control group:saline
Sponsors
Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male or female, 18-95 years old; 2. 2019 new coronavirus nucleic acid test positive; 3. Diagnosed as moderate to severe cases of new coronavirus pneumonia in 2019, which meets the following clinical manifestations: 4. With fever and respiratory symptoms, imaging shows pneumonia; 5. A severe case diagnosed with 2019 new coronavirus pneumonia, that is, any of the following: (1) Increased breathing rate (>=30 beats / min), difficulty breathing, cyanosis of lips; (2) In the resting state, it means that oxygen saturation <=93%; or blood oxygen drops rapidly; (3) Arterial blood oxygen partial pressure (PaO2) / oxygen concentration (FiO2) <=300mmHg (1mmHg = 0.133kPa); 6. I or the authorized agent signed the informed consent form; 7. Agree to collect clinical samples.
Exclusion criteria
Exclusion criteria: 1. Malignant disease in the past five years; 2. The clinical prediction is that there is no hope for survival, only cases of hospice care, or cases of deep coma that do not respond to supportive treatment measures within three hours of admission; 3. Subjects who are participating in other clinical trials or within 3 months; 4. Cases of very severe shock and respiratory failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved respiratory system function (blood oxygen saturation) recovery time; | — |
Countries
China
Contacts
Public ContactRobert Chunhua Zhao/Ronghua Jin
institute of basic medicine, Chinese Academy of medical sciences
Outcome results
None listed