Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: A novel coronavirus pneumonia patient who was more than 18 years old and agreed to participate in the trial and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Known to be allergic to hydroxychloroquine or 4-aminoquinoline; 2. Patients with severe renal insufficiency (EGFR =C,Ast > 5 times of the upper limit); 4. Suffering from retinopathy; 5. History of epilepsy; 6.G6PD deficiency; 7. Pregnancy or lactation; 8. Patients taking tamoxifen; 9. Doctors judged that this study was not in the interests of patients; 10. Transfer to another hospital which is not the study site within 72 hours; 11. Receive any trial treatment drug (off label, compassionate use or trial related) for 2019-ncov within 30 days prior to screening evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| viral negative-transforming time;30-day cause-specific mortality;co-infections;Time from severe and critical patients to clinical improvement; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day all-cause mortality;Normal time of respiratory frequency in mild to moderate disease;Improvement time of cough in mild to moderate patients;Time of oxygen saturation to normal in patients with mild to moderate disease;Time of recovery of body temperature to normal; | — |
Countries
China
Contacts
Public ContactHua Shucheng
The First Hospital of Jilin University
Outcome results
None listed