Late-life depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged >= 60 years; (2) Right handedness; (3) Meeting the criteria of DSM-V for major depressive disorder (MDD); (4) A total score of >=17 on HAMD-17; (5) A stable antidepressant dosage for at least 2 weeks prior to the study.
Exclusion criteria
Exclusion criteria: (1) A DSM-V diagnosis of other than MDD or anxiety disorders; (2) Neurodegenerative diseases; (3) History of brain trauma or brain surgery; (4) Severe physical disease; (5) Any contraindication to MRI; (6) History of epileptic seizure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Countries
China
Contacts
The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital)