postoperative atelectasis
Conditions
Interventions
Group 1:Alveolar recruitment manoeuvre, individualized PEEP and tidal volume=8ml/kg of predicted body weight
Group 2:Alveolar recruitment manoeuvre, PEEP=5cm H2O and tidal volume=8ml/kg of predicted body weight
Sponsors
Department of Anesthesiology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Male and female patients aged 18 to 85 years; 2. Body mass index (BMI) < 35 kg/m2; 3. The operation was planned under endotracheal intubation and general anesthesia, which was expected to take more than 2 hours.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or breastfeeding; 2. Moderate or severe acute respiratory distress syndrome (ARDS;PaO2 / FiO2 = 5 mg/kg/min dobutamine was required to maintain > 2.5 or suspected heart failure based on clinical symptoms (hypotension, oliguria, pulmonary edema) and nt-probnp > 13 pg /ml; 4. Diagnosis or suspicion of intracranial hypertension (> 15 mmHg); 5. Mechanical ventilation (including CPAP) required for the past 15 days; 6. A chest X-ray or computed tomography (CT) scan reveals the presence of a pneumothorax or giant pulmonary bullae (COPD) in a patient with chronic obstructive pulmonary disease, requiring oxygen or CPAP; 7. Patients participating in another intervention study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| not inflated volume;poorly inflated volume;driving pressure;PEEP;well inflated volume;over inflated volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| SPO2;arterial blood gas analysis;consumption of vasopressor;Postoperative pulmonary complications; | — |
Countries
China
Contacts
Public ContactLi Dewei
Department of Anesthesiology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed