antiplatelet drug-induced gastric and small intestinal mucosal injury
Conditions
Interventions
Treatment group A:Jinghua Weikang capsule
Control group:Placebo
Treatment group A:inghua Weikang capsule
Treatment group B:Teprenone
Sponsors
Department of Gastroenterology, China-Japan Union Hospital of Jilin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 18 years of age or older, male or female; 2. those who plan to take antiplatelet drugs; 3. those who agree to undergo capsule endoscopy before and after treatment; 4. those who have negative 13C-Hp breath test; 5. Those who have not taken other drugs that can cause stomach upset; 6. Have the ability to give informed consent, can adhere to the visit plan of this study, and can complete all study evaluations.
Exclusion criteria
Exclusion criteria: 1. Contraindications for capsule endoscopy (patients with suspected digestive tract stenosis, patients with a history of abdominal surgery); 2. Patients who refuse to undergo Helicobacter pylori-related examination and treatment; 3. Peptic ulcer, digestion Patients with gastrointestinal bleeding and other digestive diseases; 4. Patients with acute cerebrovascular disease, acute myocardial infarction, trauma, infection, suspected or confirmed diseases such as malignant tumors and hematological disorders; 5. taken within 4 weeks PPI, H2RA, antibiotics or gastric mucosal protective agents; 6. those who are treated with drugs such as glucocorticoids, warfarin, heparin; 7. severe liver and kidney damage, blood, endocrine and other diseases; 8. pregnant women And pregnant or lactating women; 9. those with mental illness or severe neurosis, who cannot express subjective symptoms, who do not follow the doctor's advice during treatment, and who cannot guarantee that the medication is completed as required during the trial; 10. those who refuse or cannot accept.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Capsule endoscopy score; | — |
Countries
China
Contacts
Public ContactJiangbn Wang
Department of Gastroenterology, China-Japan Union Hospital of Jilin University
Outcome results
None listed