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Application of nalbuphine combined with ropivacaine for ultrasound guided fascia iliaca compartment block in preoperative analgesia in elderly patients with hip fracture

Application of nalbuphine combined with ropivacaine for ultrasound guided fascia iliaca compartment block in preoperative analgesia in elderly patients with hip fracture

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029934
Enrollment
Unknown
Registered
2020-02-17
Start date
2020-02-19
Completion date
Unknown
Last updated
2020-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative analgesia in elderly patients with hip fracture

Interventions

control group:Ultrasound-guided Fascia Iliaca Compartment Block: 0.1% ropivacaine 30ml+ 2 ml 0.9% normal saline
experimental group 1:Ultrasound-guided Fascia Iliaca Compartment Block: 0.1% ropivacaine 30mL+ nalbuphine 5mg (2ml 0.9% normal saline dilution)
experimental group 2:Ultrasound-guided Fascia Iliaca Compartment Block: 0.1% ropivacaine 30ml+ nalbuphine 10mg (2ml 0.9% normal saline dilution)
experimental group 3:Ultrasound-guided Fascia Iliaca Compartment Block: 0.1% ropivacaine 30ml+ nalbuphine 20mg (2 ml 0.9% normal saline dilution)

Sponsors

Fujian Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with hip fracture (femoral neck fracture, intertrochanteric fracture) to be treated by surgery; 2. Aged >= 65 years, regardless of gender; 3. BMI 18.5-30 kg/m2; 4. Passive VAS >= 4; 5. ASA classification of I ~ III; 6. Whom sufficiently informed, and consented to the agreement.

Exclusion criteria

Exclusion criteria: 1. Allergic to nalbuphine or ropivacaine; 2. Patients who have used pain treatment drugs within 24h before surgery; 3. Patients with FICB or NSAIDs or opioid contraindications; 4. MMSE< 24; 5. Puncture site infection or ultrasound can not identify the anatomical structure or the location of the body surface; 6. History of peripheral neuropathy; 7. Coagulation dysfunction; 8. After the completion of the basic laboratory examination, the anesthesiologist will evaluate the patients with surgical anesthesia contraindication.

Design outcomes

Primary

MeasureTime frame
Degree of pain;Cycle indicators: HR, MBP, SPO2;Sensory block area;

Secondary

MeasureTime frame
Sleep quality score;Ramsay Scores;The hospital indicators;Complication evaluation;

Countries

China

Contacts

Public ContactXiaochun Zheng

Department of Anesthesiology, Fujian Provincial Hospital

Zhengxiaochun7766@qq.com+86 13705058351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026